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2294 results found

Stem cells in nasal polyposis

Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...

Imaging and management of head and neck vascular anomalies

Vascular anomalies are a diffuse spectrum of abnormalities which often involve the head, neck and oral cavity. They are frequently misnamed, often being generically labelled as haemangiomas. This lack of basic understanding can cause confusion leading to a cascade of...

ENT registrar national selection: how can we advise aspiring candidates?

With the aim of creating fair selection into the few available training numbers, ENT was one of the first surgical specialties to move to a national selection process for selecting new registrars in England. Since 2013 the selection process has...

TORS for patients with sleep-disordered breathing

Transoral robotic surgery is now a well-accepted technique in malignant tumours of the tongue base. Here the team from St Mary’s and the Royal National Throat Nose & Ear Hospital in London describe its use in carefully selected patients with...

William Hunter’s work on the anatomy of the human ear

The Hunterian Society offers an annual award for an essay and presentation on a subject of relevance to John or William Hunter, or medicine in the 18th Century. This article is based on Emma Stapleton’s 2014 winning essay, which was...

Active middle ear implants and bone-anchored hearing systems

The implantable hearing device market has grown significantly over recent years. But as conventional hearing aids improve and cochlear implant candidacy widens, what is the role for active middle ear implants and bone anchored hearing systems, and how should we...

Life Down Under: an overview of the Sydney Endoscopic Ear Fellowship

As we emerge from the impact of the COVID-19 pandemic on the first half of 2020, trainee colleagues will be looking to their future once again. Options may include fellowships, and we are delighted to have Dr Andrew Ma share...

The Laryngectomee Guide

As a Macmillan Head and Neck Specialist Nurse, I was very pleased to be asked to review this book, The Laryngectomee Guide, by Itzhak Brook, MD. It is fair to say that for most laryngectomy patients, life does go on...

What is the evidence for contralateral tonsillectomy in TORS for known unilateral tonsil malignancy?

The concept of field changes by carcinogens within the upper aerodigestive tract is well established with reported rates of synchronous tumours of 4% and second primaries of 36%. The tonsil in particular has the highest rate of synchronous tumours, postulated...

Chemo-radiation in elderly patients with head and neck cancers

Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...