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Head and neck cancer and PET-CT

Positron emission tomography-computed tomography (PET-CT) is an imaging technique in which abnormalities of tissue metabolism are precisely superimposed onto the anatomy. It relies on the premise that malignant cells are more metabolically active compared with non-malignant cells. On this basis,...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

History of photography in otorhinolaryngology in the 19th Century

In this final article of the History of ENT edition, João Clode introduces us to the history of medical photography in the 19th century, giving us some fascinating early examples of otorhinolaryngology photographs. Medical photography – the early years The...

Music and cochlear implants

Introduction The introduction of multichannel cochlear implants (CIs) in the early 1980s provided children and adults with severe and profound hearing losses with greatly improved speech perception skills. In this paper, however, I am going to focus on an area...

In conversation with Sam Lear, BAA President: leading audiology forward

Dr Samantha Lear is the current British Academy of Audiology President, and Senior Audiology Policy Advisor at the National Deaf Children’s Society. With reviews ongoing in paediatric audiology in England and Scotland, Sam is ideally placed to lead the profession....

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...