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Scientific advances in mapping syndromic hearing loss

From more than 22000 genes that we humans have, approximately 3000 genes are associated with human communication. There are tens of syndromes which have been identified to be accompanied by hearing loss. Disorders of almost every organ of the body...

Alternobaric vertigo: asymmetrical vestibular function due to asymmetrical middle ear pressures (Iron Man’s archenemy)

The Marvel Cinematic Universe could certainly be deemed an ‘extreme environment’ and yet very rarely do we see the Avenger’s popping to the clinic for a check-up. Hee-Young Kim has wondered how they cope with extreme pressure changes and discusses...

Superior semicircular canal dehiscence syndrome

In this article, Hannah North and Simon Lloyd give us an overview of the complex condition of superior semicircular canal dehiscence (SSCD) syndrome, including diagnosis, treatment and management. Superior semicircular canal dehiscence (SSCD) is a bony defect of the otic...

Microneedles enable inner ear precision medicine

Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...

Quo vadis FESS? Future directions in functional endoscopic sinus surgery

Endoscopic sinus surgery is now so ubiquitous that it is hard to imagine a time when it was not part of our clinical practice. Valentin Tomazic takes a look at its early development and looks ahead to endoscopic sinus surgery...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Family-centred early intervention: supporting a call to action

Family-centred care for young children is a commonly used but frequently under-appreciated approach in audiology. Prof Moodie discusses how we can take positive action to improve our approach to families in ways that make a meaningful difference in their lives....

Developing medical devices for children: opportunities and challenges

The development of medical devices for infants and children lags significantly behind the development of devices for adults. While in the United States the Food and Drug Administration (FDA) has set up incentives for developing child age-specific pharmaceuticals, there is...

Erasmus Darwin and the larynx – but why is it where it is and when?

Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...

Radiology and sinus disease: “the ever-evolving landscape”

Computed tomography (CT) remains the imaging modality of choice in assessment of patients with symptoms of chronic rhinosinusitis resistant to conservative treatment. In the last 10 years, CT technology has seen significant advances with the development and integration of multi-detector...