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Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

European funding for the tinnitus research network TINNET

Over 70 million people in Europe experience tinnitus, and for seven million it creates a debilitating condition. Severe tinnitus is often associated with depression, anxiety and insomnia, resulting in an enormous socio-economic impact [1]. It has been estimated that 13...

Update on the development of an implantable vestibular prosthesis

Cochlear implants have revolutionised the management of profound hearing loss. Might vestibular implants be the future for the treatment of bilateral vestibular failure? James Johnston and Neil Donnelly explore. The vestibular system is highly complex, integrating visual, labyrinthine and proprioceptive...

The Dilemma of Beethoven’s Deafness

Beethoven was one of the world’s greatest musicians, and his deafness is well known. Many details of his medical conditions are known, and various theories of his hearing loss have been proposed. Ludwig van Beethoven was born in 1770 in...

Plasticity with cochlear implants: individual factors in the outcomes

Andrej Kral gives us an overview of neuronal plasticity in congenital hearing loss, and discusses why it is core to our clinical interventions in hearing loss and rehabilitation. The brain is born immature and undergoes extensive shaping during early development....

Cochlear implantation for single-sided deafness and asymmetric hearing loss

Continuing our sub-theme of cochlear implantation candidacy, Richard Irving and Raghu Kumar review the principles and benefits of cochlear implantation in individuals who have an asymmetric hearing loss. It is well known that cochlear implantation improves auditory capacity, and in...

Alcohol and hearing

Alcohol is a well-known central nervous system depressant. Individual reactions to alcohol might vary, but the connection between alcohol consumption and tolerance to loud noise or difficulties in communication in noisy environments are well-observed phenomena; for example, at evening parties....

Robotic insertion of electrode array in cochlear implantation

Cochlear implants (CIs) are commonly used for profound bilateral hearing loss. They have specific national guidance for their insertion, however patients with a substantial residual acoustic hearing are potential CI candidates. Preservation of this residual hearing can be sought with...

Cochlear implants in the over 80s

The UK has an ageing population. Seven percent of the over 80s population have bilateral severe to profound hearing loss which can lead to associated negative outcomes (social isolation, depression and reduced quality of life). Cochlear implantation (CI) can successfully...

Advances in vestibular function testing

Vestibular function testing has historically been limited by difficulties in testing individual parts of the vestibular apparatus. Jas Sandhu describes new tests available to clinicians that address this problem. Advances in vestibular function testing Vestibular function testing has historically been...

Imaging tinnitus

Tinnitus is a common sensation with a reported prevalence of 7-32%. The British National Study of Hearing recorded that 10% of adults suffered from prolong spontaneous tinnitus, and approximately a quarter of these are subsequently referred to hospital for investigation...

What’s new in the cochlea?

Prof Furness in this article rounds up the steps and leaps being made by the scientific community to develop therapies to support, rejuvenate and / or replace the cochlear structures. David’s electron microscope images of the cochlear structures are world...