You searched for "genetic"

957 results found

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

On the influence of sex on tinnitus burden and its phenotypes

One important aspect of the new paradigm in tinnitus research is to question basic assumptions. What associations does the sex of a person have with their experience of and reaction to tinnitus? Chris Cederroth raises the question and tells us...

Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Clinical Manual of Otolaryngology

This book aims to fill the gap that many ‘generic clinical textbooks’ fail to address; the knowledge and skills required to deal with common ear, nose and throat conditions that present to general practitioners and in emergency departments. Its scope...

Hearing Health Showcase

Report by: Melanie Lough (Research Audiologist, University of Manchester) The Manchester Biomedical Research Centre (BRC) Hearing Health Showcase was somewhat of a joint celebration, with 2019 marking the 100-year anniversary of audiology and deaf education. The day began with introductions...

Radiation-induced dysphagia in head and neck cancer

This is a helpful reference paper that provides an overview of the biomolecular effects of radiation on the tissues of the upper aero-digestive tract. The authors explain that radiation injuries occur in a repetitive and accruing manner over the duration...

Rhinology and Skull Base Surgery – From the Lab to the Operating Room: an Evidence-based Approach

There have been many attempts to comprehensively address the topic of ‘Rhinology’, however Georgalas and Fokkens in their new book Rhinology and Skull Base Surgery – From the lab to the operating room: an evidence-based approach, have managed to deliver...

UEP 2018 (29th Congress of the Union of European Phoniatricians)

Report by Haldun Oguz, MD, Professor of Otolaryngology, Director, Fonomer ENT & Phoniatrics Clinic, Ankara, Turkey; President, Professional Voice Society, Turkey. One day 40 years ago, Finland hosted the seventh Union of the European Phoniatricians (UEP) Congress. Back in 1978...

Nursing care for ENT patients

Increasingly within the UK, issues related to bed availability can lead to ENT patients receiving care away from previously well-established specialist wards. This is a cause for concern in many institutions and the authors looked to assess this. They demonstrated...

The European TINNET COST Action BM1306

Winfried Schlee describes how a major European funding award is bringing together experts who are committed to collectively developing a better understanding of tinnitus. This work is vital if we are to pioneer effective treatments for the condition in its...

ESPCI 2019 - The 14th European Symposium of Paediatric Cochlear Implantation

Report by: Priya Achar, Consultant Neurotologist, Queens Medical Centre, Nottingham, UK President Luminita Radulescu organised the 15th European Symposium on Paediatric Cochlear Implantation (ESPCI). Delegates were mainly ENT surgeons, audiologists, speech and language therapists, teachers of the deaf, neurophysiologists, and...