You searched for "genomics"
Genetic discovery using animal models: presbyacusis
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...Discovery in the genetics of complex disease: Otitis media
Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...NASBS (North American Skull Base Society) 29th Annual Meeting
Report By: Gauri Mankekar, OLOL Hearing and Balance Center, Baton Rouge, Louisiana, USA The 29th Annual North American Skull Base Society (NASBS) Meeting was organised by President James Evans with co-chairs, Amir Dehdashti and Adam Zanation. Delegates consisted of neurosurgeons,...What you need to know about recent advances in genetics of hearing loss in the newborn
Identifying the underlying genetic cause of hearing loss in newborns can improve dramatically the early diagnosis and appropriate intervention. Hearing loss is the most common sensory disorder at birth, affecting approximately two out of 1000 newborns [1]. Congenital impaired hearing...Assessment of genetic disorders: congenital sensorineural hearing loss
Severe or profound sensorineural hearing impairment (SNHI) is a common birth defect, affecting approximately 1 in 1000 newborns [1]. SNHI may result from environmental causes or have a genetic basis. The genetic causes can be further subdivided into non-syndromic (isolated...
The video head impulse test: an aid to the diagnosis of spinocerebellar ataxias
Spinocerebellar and Friedreich ataxias (SCA and FA) by their nature present in neuro-otology clinics. The diagnosis is ultimately genetic but the authors investigated the characteristics of the VOR using the video head impulse test (vHIT) in order to distinguish between...Hearing Health Showcase
Report by: Melanie Lough (Research Audiologist, University of Manchester) The Manchester Biomedical Research Centre (BRC) Hearing Health Showcase was somewhat of a joint celebration, with 2019 marking the 100-year anniversary of audiology and deaf education. The day began with introductions...Innovative approaches to treating deafness
Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...Staphylococcus aureus as a cause of refractory chronic rhinosinusitis
Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...SFO Conference 2021
The Student and Foundation Doctors in Otolaryngology (SFO) Conference 2021 kicked off to a great start with a very warm welcome from SFO UK Chair Mr Dheeraj Karamchandani and Professor Nirmal Kumar, ENT UK President. The friendly and encouraging tone...Annual Activity of The British Association of Audiovestibular Physicians 2021
The British Association of Audiovestibular Physicians (BAAP) is the national association of Auiovestibular Physicians in the UK. The Education Committee and the Audit Committee of BAAP organise a range of thought-provoking events annually. As we embraced a new way of...
