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Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Aerosol research and performance

Is singing safe? This was a question asked around the world at the start of the pandemic in early 2020. Natalie Watson and Chris Orton tell us about a rapidly-convened research group that led to profound changes in UK Government...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Otoacoustic emissions in the diagnostic test battery for hearing loss

So, they are great for screening, but how can otoacoustic emissions be integrated into the diagnostic test battery? Beth Prieve examines the role of diagnostic OAEs by asking three simple questions. Audiologists and otolaryngologists are familiar with otoacoustic emissions (OAEs)...

Hearing loss prevention in musicians - violating one rule of physics

Whilst enjoying music, we also need to be mindful of the potential effect of producing music for the musician. Dr Chasin discusses the development of earplugs for the industry with the added bonus of physics for party goers! Hearing protection,...

Sugammadex

Scott Russell is an anaesthetist with an almost unrivalled experience of complex head and neck surgery, and has seen all manner of new ideas come and go. However, in this article he describes a new pharmaceutical agent that is already...

How trainees can make major contributions to practice

At a time when many of our trainees feel poorly supported and disheartened, the formation of a National ENT Trainee Research Network (Integrate) has been a major advance, enabling them to develop and execute research projects directly relevant to clinical...

The role of training programmes in protecting patients

ENT trainees are fully registered doctors who have responsibilities to comply with the requirements of Good Medical Practice. This includes ensuring that they put the interests of their patients at the heart of their practice. This duty is complementary to...

Intratympanic treatments for subjective idiopathic tinnitus

Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...