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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...
How does endoscopic surgery for subglottic stenosis affect voice outcomes?
Patients with subglottic stenosis (SGS) require interventions to improve their breathing and airway patency. Increasingly, these interventions are completed endoscopically but little is known about how endoscopic surgery impacts voice outcomes. The authors of this study completed a systematic review...The doctor – pharmaceutical company relationship
‘Which drug rep is taking us out tonight?’ We have heard this phrase uttered at conferences since meetings began, but as Dylan said ‘those times they are a changing’ thanks to the Association of the British Pharmaceutical Industry (ABPI) and...
Rates of tonsillitis increase as rates of tonsillectomy reduce
This retrospective study sought to determine the effect of reduced rates of tonsillectomy in England and Wales, over a 13-year period, on rate of hospital admissions for the complications of acute tonsil infection (acute tonsillitis and quinsy), and hospital bed-day...BLA: An Introduction to the Voice Clinic: Case Discussions and Practical Skills
The BLA are holding a Voice Clinic day: ‘An Introduction to the Voice Clinic 2025 – Case Discussions and Practical Skills’. This will be held on Monday 3 March 2025 at Wythenshawe Hospital, Manchester. This course is designed for ENT...Returning to practice
Here, we provide a combination of written guidelines, podcasts and videos providing information on returning to practice and elective services during the COVID-19 pandemic. Resources will be updated as and when they become available. - Guidelines - 7 July -...Database WG2. The Tinnitus Patient Database in the TINNET COST Action BM1306
Berthold Langguth describes an innovative project that is creating the world’s largest multi-national patient database containing standardised information on tinnitus and medical history, otological examination and psycho-acoustic measures of tinnitus. A challenge for tinnitus treatment and tinnitus research is the...Endoscopic middle ear surgery for cholesteatoma treatment
A critical question when any new technique is proposed is ‘does it work?’ In this article Daniele Marchioni and Davide Soloperto discuss the success rates of endoscopic ear surgery for cholesteatoma. Introduction Surgical management of cholesteatoma is still a controversial...
Predicting which oropharyngeal SCC HPV-positive patients should avoid de-escalated treatment
This study is timely for many reasons and raises very important questions in the management of the current rise in HPV-positive patients with oropharyngeal cancer (OPC). The uniqueness of this group within head and neck cancer in terms of favourable...
The role of imaging in differentiating rare temporal bone neoplasms
This paper provides a useful tool to assist in determining the diagnosis of benign neoplasms of the temporal bone using readily available imaging modalities. Specifically, this group have looked at chondrosarcoma, an expansile hypermetabolic mass lesion usually found in the...
Voice outcomes following extended laser resections for laryngeal cancer
It is now widely accepted that the oncological and voice outcomes following transoral laser microsurgery for early T1a glottic cancers are equivalent to, if not superior to, traditional radiotherapy. Voice outcomes following more extensive resections have not been as frequently...
