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Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?

COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...

The PMFA Journal - April/May 2019 issue available

FEATURES IN THIS ISSUE: An update on BIA-ALCL by Shadi Ghali / The importance of teamwork and leadership in the management of patients in burns centres by Emily Claire Taylor, Steven LA Jeffery / Focus: Opinions on regulation by Dalvi Humzah, Paul Charlson, Andrew Rankin / CPD certified: Hand rejuvenation with injectable fillers by Medhat Abdelmalek AND MUCH MORE...

GN to help millions of Americans with unaddressed hearing loss thanks to the new OTC hearing aid category

Following the release of the OTC hearing aid regulations by the FDA on Tuesday 16 August, GN have announced their support of the ambition to help more people access hearing aids.

In conversation with George Browning, author of Browning’s Audiology for Clinicians

Professor George Browning. It is one of those superbly bright August mornings in London’s West End. It gives Lamb’s Conduit Street, where I’m meeting George Browning, an almost timeless feeling. The café we meet at is bustling and noisy, and...

In conversation with George Browning, author of Browning’s Audiology for Clinicians

Professor George Browning. It is one of those superbly bright August mornings in London’s West End. It gives Lamb’s Conduit Street, where I’m meeting George Browning, an almost timeless feeling. The café we meet at is bustling and noisy, and...

Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?

Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...

Swallowing outcomes following partial laryngectomy: objective assessment and pre-operative predictive factors

Partial laryngectomy constitutes one of the treatments for early stage glottic carcinoma (i.e. T1N0 and T2N0) in specialised centres. Over the years, several partial laryngectomy and reconstruction techniques have been described in the literature. The choice of technique depends on...

British Skull Base Society Clinical Consensus Document on Management of Head and Neck Paragangliomas (HNPGLs)

All forms of HNPGLs should be managed by a multidisciplinary team (MDT) of core members from skull base otolaryngology, head and neck surgery, clinical genetics, oncology, endocrinology, vascular surgery, radiology and pathology. Extended members include neurosurgery, endocrine surgery, nuclear medicine,...

Quo vadis FESS? Future directions in functional endoscopic sinus surgery

Endoscopic sinus surgery is now so ubiquitous that it is hard to imagine a time when it was not part of our clinical practice. Valentin Tomazic takes a look at its early development and looks ahead to endoscopic sinus surgery...

Ronald G Macbeth – the instigator of BACO

The structure of BACO has changed dramatically since the first conference in 1963, but the fundamental elements of academic excellence, instructional sessions and social events have been common threads. Andrew Freeland, who worked with Ronald Macbeth, the instigator of BACO,...

Otological problems in musicians

Musicians are understandably anxious about their hearing, and recent high-profile cases of noise-related hearing loss have resulted in huge changes in the music industry. Chris Aldren (otologist and violinist) explains. In the recent Oscar-winning movie, Sound of Metal, heavy metal...