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Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...Laryngeal papillomatosis
Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...
Analysing videofluroscopy: does it matter how it’s done?
Videofluoroscopy, as a tool that assesses the process of swallowing, has transformed our understanding of dysphagia. Clinicians can observe the biomechanics of a bolus moving from the oral cavity through the pharynx and oesophagus and into the stomach. Over the...Tribute to the late Douglas Pitman, Founder DP Medical
Rob Atkinson, Chief Executive of DP Medical Systems, said: “It is with great sadness that we announce the recent death of our company founder and namesake, Douglas Pitman, on Saturday 6 September 2025, after a long illness. The late Douglas...The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...The effects of leisure noise exposure on young people’s hearing
There is growing concern regarding the effects of leisure noise exposure on young people’s auditory system. Information provided by healthcare professionals should be evidence-based; Hannah Keppler discusses some recent findings about hearing in young people. Excessive noise exposure can lead...The evolving role of OAEs in newborn hearing screening
An admission on emissions from James Hall! OAEs hold an established place in the screening of infants; Professor Hall introduces how OAEs established this position and the advances keeping the test relevant to today’s infant screening battery. Introduction Truthfully, when...Otoacoustic emissions in the diagnostic test battery for hearing loss
So, they are great for screening, but how can otoacoustic emissions be integrated into the diagnostic test battery? Beth Prieve examines the role of diagnostic OAEs by asking three simple questions. Audiologists and otolaryngologists are familiar with otoacoustic emissions (OAEs)...Transnasal oesophagoscopy (TNO) and balloon dilatation under a local anaesthesia
Many of us are becoming more and more familiar with the use of transnasal oesophagoscopy. It has a number of well-described uses in the outpatient setting and is well tolerated by our patients. Yakubu Karagama describes taking this technique a...
Vocal fold motion impairment following intubation – how likely is it to recover?
Ed’s Choice reviews a timely paper investigating prolonged intubation on vocal fold motion. The current scientific literature is dominated by studies examining COVID-19 and its widespread effects on health and healthcare delivery but will be old news by the time...
Paroxysmal downbeating nystagmus and proton pump inhibitors
This case report highlights the effect of long-term use of proton pump inhibitors on the vestibular system. The authors reported a case of a 70-year-old woman who was admitted with delirium, ataxia, slurred speech and slowness of thought. She had...
