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Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?

Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...

Effect of COVID-19 on hearing and balance

Rhinological symptoms are cardinal features of COVID-19. However there have only been anecdotal reports on the involvement of the ear, the closest neighbour to the nose and throat. The aim of this study was ‘to assess the presence of persistent...

Complications associated with intra-tympanic steroid injections for sudden sensorineural hearing loss

Around 15,000 people in the UK experience a sudden sensorineural hearing loss (SSNHL) each year, and in the majority of cases the cause is unknown. Treatment options for idiopathic SSNHL include various modalities of steroid treatments which have known limitations...

Blood-sampling prognostic predictors for Bell’s palsy

Bell’s palsy is generally defined as an acute-onset unilateral idiopathic mononeuropathy in the facial nerve. It is of unknown aetiology, however, inflammation is considered a major cause. Electroneurography assessing nerve excitability is the most reliable examination for predicting prognosis of...

Validating a new international cholesteatoma classification – a necessary but challenging task

A European and Japanese joint consensus statement was published in 2017 which proposed a new cholesteatoma staging classification (EJS), with four stages. This follow-up publication aims to assess the internal and external validity of the staging system using existing prospectively...

Systematic review and meta-analysis showing benefit of cochlear implantation in adults with single-sided deafness

This article presents results of a systematic review and meta-analysis to further investigate the impact of unilateral cochlear implantation (CI) in adults with single-sided deafness (SSD) with regards to speech perception in quiet and noise, tinnitus, sound localisation and quality...

Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer

The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...

International classification of bilateral vestibulopathy (BVP)

In the past few years the Bárány Society have been standardising the diagnostic criteria for various vestibular disorders – International Classification of Vestibular Disorders (ICVD). Diagnosis of BVP relies on history, bedside clinical assessment and objective vestibular tests. The authors...

Voice after posterior cordotomy: we think voice is bad, patients think it’s better!

Bilateral vocal fold immobility (BVFI) is a condition that can affect voice with an impact on quality of life (QOL). Surgical trauma from damage to bilateral recurrent laryngeal nerves, such as from previous thyroid, parathyroid, or mediastinal surgery are common...

Acute peripheral vestibulopathy: is it really neuritis?

The pathophysiology of acute vestibular dysfunction has been debated for decades. By seeking to clarify the underlying aetiology, this study muddies the waters further by advocating systemic and intratympanic steroids as first line treatment if the aetiology is uncertain. The...