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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...Staying safe during endoscopic ear surgery
There is growing interest in using rigid endoscopes rather than traditional operative microscopes to perform transcanal middle ear surgery. Rigid endoscopy provides a high resolution, wide-angle view of the tympanic cavity through minimally invasive surgical portals. In this article, Elliott...Fifteen years of vestibular implant research in humans
Implants: it’s all in the balance! Prof Guyot and his team give us an update on their research in addressing bilateral vestibular deficits via an implant. Doctors are often unaware that people, even young, may lose vestibular function on both...
Assessing Middle Ear Function in Infants
This book fills a significant void in the clinical literature. There are key reference texts for each area of clinical work which should be on every departmental bookshelf, and Assessing Middle Ear Function in Infants joins that list. It might...
Head and Neck Ultrasonography Essential and Extended Applications – 2nd Edition
This is a very well-written and much-needed second edition to the original book. The author focuses on the head and neck ultrasonography from an ENT surgeon’s perspective. The text is very reader-friendly. The book focuses on the basic and extended...
Endoscopic Approaches to the Parsanasal Sinuses and Skull Base
This is an excellent book to cover the endoscopic approaches to the paranasal sinuses and skull base with a step-by-step anatomic dissection guide. The editors are a group of eminent skull base otolaryngologists and neurosurgeons in Barcelona, Spain, and they...
Laryngeal Cancer: Clinical Case-Based Approaches
This book, published by Thieme, provides a lot of information in a compact size. I enjoyed reading the book as it has an international list of authors and contributors from South America, USA, Europe and Asia which gives it an...
Healthcare economics and device approvals
We use several FDA-approved devices in our clinical practice but are rarely aware about the stringent procedures followed by manufacturers, as well as the FDA, before the devices become commercially available. The authors of this paper undertook a comprehensive review...
Do intratympanic injections require local anaesthesia?
Intratympanic injections are becoming increasingly acceptable in the management of Meniere’s disease, tinnitus and sudden hearing loss. This is because they avoid the need for hospitalisation and can be performed as low-cost outpatient procedures. It is traditional to freeze the...
Do tonsillotomies have a higher revision rate than tonsillectomies?
Tonsillotomies have gained popular acceptance in children with sleep-disordered breathing (SDB) in recent years. Short-term advantages that have been shown in the literature include lower haemorrhage rates, shorter operation times and less pain. Evidence for long-term effects are sparse due...
A new bio-glue for neurosurgical wound closures
Dural closures need to be tight to prevent cerebrospinal fluid leaks. Traditional wound closure techniques involve sutures and DuraSeal which is the only FDA approved polyglycol hydrogel sealant with proven safety and efficacy profile. This article describes a new sealant,...
