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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...ENT and evidence-based medicine: How do they benefit each other?
How do we assess evidence, and how should ENT surgeons use EBM? Evidence-based medicine (EBM) is the practice of medicine based upon high quality scientific research. There are several formal definitions of EBM, the most widely quoted being that of...
Liver function assessment in glandular fever
This month’s Editors’ Choice is a systematic review of the role of liver assessment in patients with glandular fever. Admission of patients with sore throat constitutes a significant burden of acute work for paediatric and adult ENT services as well...
Association between Meniere’s disease and vestibular migraine
Meniere’s disease (MD) and vestibular migraine (VM) are two conditions with overlap in their symptoms. There is often a lack of understanding regarding symptom-based differentiation between them. MD presents with episodic vertigo, fluctuating hearing loss and tinnitus. MD has been...
What to do if adenotonsillectomy does not cure sleep apnoea in children?
This article reviews the management of children with persistent obstructive sleep apnoea (OSA) following adenotonsillectomy (AT). Risk factors for patients to have persistent disease include obesity, being Afro-Caribbean and existing co-morbidities such as craniofacial and neuromuscular disorders. Initial assessment of...Radiology and sinus disease: “the ever-evolving landscape”
Computed tomography (CT) remains the imaging modality of choice in assessment of patients with symptoms of chronic rhinosinusitis resistant to conservative treatment. In the last 10 years, CT technology has seen significant advances with the development and integration of multi-detector...Deaf scholar is UK first
The first deaf scholar ever to achieve full professor status in the field of deaf studies and sign language studies in the UK has been announced at Heriot-Watt University in Edinburgh.What is Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)?
THRIVE is a physiological mechanism for oxygenating and ventilating patients who are under general anaesthesia and who have diminished or absent respiratory effort [1]. Classical ventilation requires bulk flow of gases into and out of the lungs driven by chest...
Management of smell and taste disorders – A practical guide for clinicians
This textbook with 240 pages is well laid out, very well illustrated including colour photographs and has excellent summary boxes at the end of individual sections. Up to one fifth of adults have some form of olfactory dysfunction and as...
How young is too young for tympanoplasty?
This paper presents the largest series of pre-school age children undergoing tympanoplasty compared with older children. The authors have collected much prospective data on 259 children undergoing 284 surgeries so were able to perform multivariate analysis. The age groupings of...
Do you feel me? Emotional processing post-traumatic brain injury
Traumatic brain injury (TBI) accounted for just under three million accident and emergency admissions in the US in 2013, with common causes including falls, traffic accidents and assaults. Difficulties processing and expressing affective communication is a common sequela of TBI...
