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Endotypes in chronic rhinosinusitis: clinical relevance
Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...Timing of surgery in chronic rhinosinusitis: does it matter?
While many patients with chronic rhinosinusitis respond to medical treatment, some do not. The next step for these patients is surgery, but how soon should this be offered? Sooner rather than later seems to be the answer, as Claire Hopkins...
Impact of the updated cancer staging system on HPV-positive disease
The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...The making of a paediatric airway surgeon: In conversation with David Albert
Michael Kuo interviews David Albert to find out what drew him to paediatric airway surgery, the mentors who shaped his surgical approach, and to ask his advice for budding young paediatric airway surgeons. David Albert. When did you first get...Hearables: in-ear sensing devices for recording of physiological signals
Colver Ken Howe Ne, Jameel Muzaffar and Manohar Bance discuss the potential of hearable systems to monitor physiological signals (e.g. from brain or heart, blood pressure, body temperature) unobtrusively. Such adaptations require high-quality sensors and sophisticated de-noising signal processing on...
Polypharmacy in the vestibular clinic
Polypharmacy is defined as the simultaneous use of five or more medications and its prevalence is increasing. Dizziness or vertigo are common side effects of polypharmacy. Despite advancements in patient data management, there remains limited information on polypharmacy in patients...Current considerations on neural development and hearing loss in young children
The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...
IFTTT.com: a recipe for success with hearing aids?
Technology simplifies our lives: agree or disagree? For me, the answer to that statement can vary quite a bit throughout any given day. As much as I am now able to communicate, check my bank account, share photos, and find...
A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
