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Molecular and genetic nature of skull base tumours drives management

This article reviews the molecular basis and paradigm shift in the diagnosis and management of skull base tumours. It is now known that the phenotype of meningiomas is influenced by their genotype. Endolymphatic sac tumours are observed in up to...

Genetics of IP-III

The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...

In conversation with David Baguley

A reflective discussion with a scientist-practitioner in tinnitus David Baguley has worked in audiology at Addenbrooke’s Hospital since 1985, becoming the Consultant Clinical Scientist in 1989. In 2006, David received an International Award in Hearing from the American Academy of...

The connection between hearing loss and cognitive decline: current perspectives

Lilian Felipe examines how age-related hearing loss accelerates cognitive decline and raises dementia risk, highlighting the importance of early detection and intervention. Introduction Hearing loss has traditionally been regarded as a routine component of the ageing process. Over the past...

Patron saints of the ear

We all know that ear symptoms include hearing loss, vertigo, tinnitus and otalgia, but did you know there are patron saints for all these symptoms? John Riddington Young shares an overview of the patron saints of the ear, inspired by...

From the editor Sep/Oct 2025

Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. TW / X: @Voicedoctor_uk Here at ENT & Audiology News, we like to celebrate clinicians at all stages of their careers. For Sep/Oct 2025,...

A mouth-rinse test that can screen for oral cancer?

This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...

Transnasal oesophagoscopy in head and neck cancer: an update

The role of transnasal oesophagoscopy (TNE) in the management of head and neck cancer patients is evolving. Until 1990, oesphagoscopy required specialist endoscopists, general anaesthesia or sedation. This review succinctly summarises updates in the evidence for TNE in: i) Screening...

Role of fine needle aspiration cytology in the management of thyroid neoplasm

Fine needle aspiration cytology (FNAC) is a useful procedure in the assessment of thyroid swellings. This retrospective study was done at King Abdul-Aziz University hospital, King Saud University, Riyadh. The objectives of this study were: to determine the cytological pattern...

A time-saving method for faster cancer diagnosis and treatment

One of the main impediments in achieving UK Government cancer diagnosis and treatment targets is lack of diagnostic capacity. An increase in head and neck cancers by 50% in the last five years has put on additional strain. In this...

BACO – the early years

The origins of the British Academic Conference in Otolaryngology (BACO) are indelibly intertwined in the mists of time with the foundation of the British Association of Otolaryngology (BAO). For further information on the latter I can only refer the interested...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...