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High dose betahistine as effective as, but slower acting compared to intratympanic dexamethasone in intractable Meniere’s disease

The management of intractable Meniere’s disease poses a complex conundrum to otolaryngologists. The focus of treatment is decreasing the severity and frequency of vertigo and tinnitus whilst trying to preserve hearing. Betahistine has been used for many years in the...

Local dexamethasone infiltration in tonsillectomy

Intravenous dexamethasone is routinely given during tonsillectomy for its effects on postoperative pain and nausea. This Chinese randomised study divided 240 children undergoing tonsillectomy into three groups, receiving either no steroid, intravenous dexamethasone, or the same amount of dexamethasone infiltrated...

Sphenopalatine ganglion block in endoscopic sinus surgery reduces intra and post-operative morbidity

The authors present results of a meta-analysis to investigate the role of sphenopalatine ganglion block (SPGB) in reducing postoperative pain in endoscopic sinus surgery (ESS). An electronic database search (Pubmed, SCOPUS, Google Scholar, Embase, and the Cochrane Register of Controlled...

Nasal polyps, does size matter?

This study from Germany investigates the correlation between nasal polyp size and return of olfactory function following endoscopic sinus surgery. Olfaction is affected more in patients with CRSwNP than with CRSsNP and the best chance of smell recovery occurs in...

Hear me out – tiny steroid implants for fighting meningitis-induced deafness

Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

EEG as a measure of neuroplasticity in children

Measuring changes in neural activity can teach us a lot about hearing loss and the effect of gained functional hearing. In this article, the authors describe how electroencephalography (EEG) is being used to effectively measure such changes in children with...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Detecting hearing loss in the military: are the current methods adequate?

A team at the University of Southampton have been funded by the Ministry of Defence to investigate how to improve the assessment of auditory fitness for duty in the UK Armed Forces. Matt Blyth talks us through the current methods...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

Barriers to cochlear implantation in low resource settings

The benefits of early detection and rehabilitation of hearing loss in children, especially through cochlear implantation, are unequivocal. However, access to these valuable resources is far from equal and universal. Identifying the barriers is the first major step in addressing...

Why does music move us? Music as auditory signals of emotion

Music forms an integral part of the lives of people in all known cultures around the world. In this article Dr Sandra Garrido explains that in fact, our response to music is largely innate and is related to the evolutionary...