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Vitamin C, a possible remedy for seasickness?
The internet is full of devices and medicines vying for superiority over which one is the best for preventing seasickness. This study was based on the following observations: elevated histamine levels trigger seasickness; blockade on histidine decarboxylase prevents seasickness while...
Be sober to stay on your feet
Readers would either have had a personal experience or observed the inelegant gait of the inebriated. Re-aligning the body during postural perturbations involves changes in head position, shoulders, and hip, knee and ankle joints. The main hypothesis of this study...
Swallowing outcomes following partial laryngectomy: objective assessment and pre-operative predictive factors
Partial laryngectomy constitutes one of the treatments for early stage glottic carcinoma (i.e. T1N0 and T2N0) in specialised centres. Over the years, several partial laryngectomy and reconstruction techniques have been described in the literature. The choice of technique depends on...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...
Endoscopic myringoplasty: a promising alternative to microscopic surgery
Endoscopes have revolutionised otitis media surgery in recent years and are increasingly used in the surgical management of cholesteatoma, sinus tympani pathology and facial nerve surgery. Despite this, the development of endoscopic myringoplasty and how this compares to its microscopic...
Occlusal splint, injections or arthrocentesis in myofascial pain
Facial pain is a fairly common complaint and may present in a myriad of symptoms. These patients present to both dentists and general practitioners and could end up referred to a number of specialists. Temporomandibular disorders may originate from either...
Does Eustachian tube dysfunction improve with FESS?
This multinational study prospectively collected SNOT-22 data to determine the prevalence and severity of, and whether endoscopic sinus surgery (ESS) had improved, symptoms of Eustachian tube dysfunction in patient with chronic rhinosinusitis (CRS). The SNOT-22 includes two questions which are...
Occupational dust exposure and nasal polyposis
This interesting European cross-sectional study demonstrates a link between occupational dust exposure and the presence of nasal polyposis. A random sample of textile workers (215) and retail store employees (101) in Portugal was taken, with clinical data gathered through a...
Predicting CSF leaks pre FESS: Gera classification - a new tool?
An interesting study from Italy looking at an anterior skull base classification that may be useful in predicting risk of intraoperative CSF leak during FESS surgery. Traditionally we have used the Keros classification system, developed in 1962 to categorise olfactory...
CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...
Validating a new international cholesteatoma classification – a necessary but challenging task
A European and Japanese joint consensus statement was published in 2017 which proposed a new cholesteatoma staging classification (EJS), with four stages. This follow-up publication aims to assess the internal and external validity of the staging system using existing prospectively...
