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Vicarious (nasal) menstruation

Hippocrates himself is known to have said that when a woman’s menses are due, but instead of the usual vaginal menstrual flow, she has a haemorrhage from the nose, then this is a sure sign of pregnancy [1]. Artist’s impression...

Medical Journals and The Journal of Laryngology and Otology

Medical journals have a fascinating history. One early journal, The Lancet, was founded in 1823 and its first Editor, London surgeon Thomas Wakley (1795-1862), had a turbulent life. He lived in an era where quackery was rife and where the...

The artificial eardrum: how an eggshell membrane fed a German ENT family

In the pre-antibiotic era, purulent otitis media often resulted in a permanent eardrum perforation with hearing loss. In addition to pig or fish bladders, eggshell membranes and cigarette paper were used as eardrum prostheses. I have vivid personal boyhood memories...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Chronic cough hypersensitivity syndrome

We all have patients who give us a ‘heartsink’ feeling; for many of us, the coughing patient is exactly such a situation. In this overview, Bhaskar Ram and Sangeeta Maini outline their approach to diagnosis. Declan Costello, Editor. Introduction Chronic...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...