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1880 results found

Allergy and the ear

Allergic disease is commonly associated with asthma, eczema and rhinosinusitis. The authors reviewed possible associations between allergy and otologic diseases. The authors first explored the possible association between allergy with otitis media with effusion (OME) and found the majority of...

CRSwNP and smell – is it just the obstruction?

Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

Facial nerve anatomy in the temporal bone

Knowledge of the facial nerve anatomy during otological surgery is crucial in avoiding an iatrogenic injury to the facial nerve. In this study, the authors investigated the anatomical relationship between the tympanic portion of the facial canal (FC) and the...

Ear wax removal: should anyone and everyone perform it?

Earwax removal is a controversial and much-debated issue in audiology. Risks and public safety call for reforms, sparking discussion on professional standards. Earwax is a natural secretion produced by the ear. It is an amalgamation of desquamous epithelial skin cells,...

Intracranial complications of otitis media – the difference between kids and adults

Despite a decrease in intracranial complications from otogenic infections since the introduction of antibiotics, there is still morbidity and mortality associated with this. This group from the Netherlands conducted a retrospective review of all the patients treated for intracranial complications...

Rhinology and Allergy: Clinical Reference Guide

This pocket-sized book aims to provide a clinical reference guide through a series of review chapters. The editors, Brent A Senior and Yvonne Chan, have produced a comprehensive text through the work of predominantly North American and Canadian co-authors of...

Myringoplasty in a bottle?

Management of large traumatic TM perforations can involve observation and water precautions or surgical repair. Closure rates for larger perforations can be 8-12 weeks and occurs for between 38-79%. Animal and human studies have shown that exogenous application of epidermal...

William Hunter’s work on the anatomy of the human ear

The Hunterian Society offers an annual award for an essay and presentation on a subject of relevance to John or William Hunter, or medicine in the 18th Century. This article is based on Emma Stapleton’s 2014 winning essay, which was...

Laryngotracheal stenosis

Airway stenosis has been an enormous challenge to laryngologists since the dawn of the sub-specialty. Careful evaluation is essential, as this will determine the best treatment. We hear more from one of the UK’s leading airway centres. Until the advent...

Supporting the definitive diagnosis of LPR

Voice disorders affect one in 25 people in the UK, and laryngopharyngeal reflux (LPR) is a common culprit. LPR occurs when the stomach contents – including strong digestive enzymes like pepsin – flow back up into the throat, causing inflammation...

Role of intranasal steroids after radiotherapy for nasopharyngeal carcinoma

Rhinosinusitis often follows radiotherapy in the treatment of carcinoma of the nasopharynx. The interval and severity may vary with the dose of radiation and stage of the carcinoma. In this randomised, controlled study, patients who developed rhinosinusitis after radiotherapy treatment...