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Nasal nitric oxide – an inflammatory marker in paediatric allergic rhinitis?

Nasal nitric oxide (nNO) is mainly produced in the paranasal sinus mucosa and was shown in some studies to have increased expression in allergic rhinitis (AR). Although it represents a potential non-invasive tool for AR measurement, there remains no consensus...

Adenoidal hypertrophy in children with allergic rhinitis

Nasal congestion in children with allergic rhinitis can be confounded by adenoidal hypertrophy. This retrospective Turkish study examines this association in more detail. The sample studied was 566 children (age 2-18) that were diagnosed (based on ARIA guidelines) and treated...

Mastoid obliteration for canal wall down surgery

Surgery for acquired cholesteatoma is varied amongst surgeons with some only performing combined approach tympanoplasty. The change in lifestyle for patients with canal wall down surgery is significant and hence this group in Japan looked at 118 adult patients with...

CRSwNP and smell – is it just the obstruction?

Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

3D-printed temporal bone models - how good can they be?

In the era of increasingly difficult and expensive-to-come-by cadaveric temporal bones with which to practise drilling and learn the complex 3D anatomy of the temporal bone, decent alternatives would be welcome. McMillan et al report a prospective comparison study in...

NEW: Simple Yet Powerful Hearing Amplifier

BeHear® SMARTO provides out-of-the-box hearing amplification for people with mild to severe hearing loss.

From the editor SepOct 2021

As the pandemic evolves, the world seems to be divided into those countries that are fortunate enough to have good vaccine coverage and, hence, are able to open up their societies; and those who do not have an adequate vaccine roll-out and are having to live with significant restrictions or high levels of prevalent disease.

Paediatric auditory brainstem implant: overview and outcomes

Auditory brainstem implants were first used in adults with NF2. They have more recently become a technology option for children but what is the evidence to support this choice? This article discusses the evidence so far. Auditory brainstem implant is...

The totally implantable cochlear implant

*The authors are in alphabetical order – both authors are first authors on this publication A groundbreaking fully implantable cochlear implant marks the start of a new era in hearing restoration – discreet, continuous and free from external hardware. The...

Surgical management of congenital nasal pyriform aperture stenosis

Introduction Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of neonatal upper airway obstruction which was first described by Douglas in 1952 [1]. The first radiological description of CNPAS was described by Ey et al in 1988 [2]....

The common frontal sinusotomy (Lothrop) and chronic rhinosinusitis

As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...