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The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...In conversation with Professor Gerry O’Donoghue
On the occasion of his retirement from the Nottingham Auditory Implant Programme, we discuss his pioneering work in cochlear implantation and the challenges involved. ENT News author picture, 1993. Why did you choose a career in ENT? I started off...Audiology and ophthalmology: a comparative perspective on diagnostics and patient care
What are the similarities and differences between audiology and ophthalmic practices, and what can we learn from each other? Rosalyn Painter finds out. I’m here with Chris Gordon and Anthony Vukic from Gloucestershire Hospitals NHS Foundation Trust to find out...
A comparison of same day with staged bilateral cartilage graft tympanoplasty for tubotympanic CSOM
This randomised, controlled study compares the tympanoplasty outcomes in two groups of patients: one undergoing bilateral tympanoplasty on the same day (18 patients, 36 ears) and the other having the same procedure done on different days, with a gap of...
Does post-meningitic cochlear obliteration affect impedance and charge of the implant?
Implantation in children deafened by meningitis may be very challenging due to obliteration or ossification of the cochlea. This study aimed to assess impedance values and charge consumption in such cases and evaluate if they are affected by the degree...
Quality of life after FESS or balloon sinuplasty
This randomised control trial compared the SNOT-22 questionnaires both pre-operatively and three months post-operatively in patients with chronic rhinosinusitis undergoing either FESS or balloon sinuplasty to the maxillary sinus. Forty two patients participated in the study, 21 in each treatment...
Is there a role for hyperbaric treatment in sudden hearing loss?
Sudden sensorineural hearing loss is a common presentation to ENT departments with a significant difference in management both at a local and regional level. The authors seek to clarify the role of hyperbaric oxygen therapy in combination with oral and...
CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
The GP and the ear
General practitioners are the first members of the medical community to deal with ear problems. In this survey, 11 GPs examined 124 patients using a regular otoscope and a video-otoscope and reported their findings in a 10-item table. The same...
Outcomes following endoscopic vs. microscopic ossiculoplasty
Endoscopic ear surgery continues to increase in popularity with an expanding range of applications in otology. The variety of angled scopes allow for superior visualisation of the surgical field and difficult to reach areas. However, use of endoscopes reduce the...
Tympanostomy tubes outcomes by tympanic quadrants- a meta-analysis
Tympanostomy tube (TT) insertion is one of the most common ENT procedures, resulting in millions of TTs being implanted per annum and occurring complications that need to be addressed. Premature TT extrusion (PTTE) is a well-recognised such complication, affecting almost...
