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Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

A new hydrogel dural sealant for CSF repair

This paper reports the findings of a multicentre prospective randomised trial conducted to demonstrate the efficacy of the Adherus Dural Sealant for FDA approval. The Adherus Dural Sealant was compared with the control, DuraSeal Dural Sealant. It was applied to...

Audiology and speech language pathology programmes in India: an overview of education and career opportunities

This article is provided by Lalsa Shilpa Perepa, a Clinical Audiologist who started her audiology career in India. Audiology and speech language pathology (ASLP) courses in India are offered by various colleges and institutes that are affiliated with different universities...

A soprano’s demise: a cautionary tale for the thyroid surgeon

Prior to the mid-19th century, thyroid surgery was considered excessively dangerous. The emergence of anaesthetic, antisepsis and improved instrumentation, however, increased its feasibility and frequency in Europe. The unhurried, judiciously antiseptic and haemostatic approach, advocated by Kocher, was popularised and...

Climate change and global health

As we put together the Editors’ Choice for Jul/Aug 2022 Journal Reviews, news from a meeting of the G7 energy and environment ministers has been shared that the G7 countries are to stop public funding of any overseas fossil fuel...

The Temporal Bone: Anatomical Dissection and Surgical Approaches

The Temporal Bone: Anatomical Dissection and Surgical Approaches does exactly what it says on the tin. It is an excellent combination of anatomical atlas and dissection manual for temporal bone surgical procedures, designed to be kept open at the benchside...

Hear me out – tiny steroid implants for fighting meningitis-induced deafness

Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...

A safe and useful surgical procedure for allergic rhinitis?

Although the best management of allergic rhinitis is medical, intractable cases are not uncommon. Immunotherapy helps but is more practical if there is a single allergen involved. The authors compare the effects of submucosal inferior turbinoplasty alone with submucosal turbinoplasty...

An overview of human factors in ENT and anaesthesia

James Bates and Chris Frerk are both passionate about how human factors science can improve safety in healthcare and have co-authored this article describing how communication, ergonomics and other non-technical skills are making operating theatres safer. There is no doubt...

Managing the most common branchial arch anomaly

This article is a well written, helpful summary of the management of the most common branchial anomaly in children – the second. These are characterised as cysts, sinuses or tracts between the anterior border of sternocleidomastoid, coursing between the internal...

Protheses for patients with severe bilateral vestibular loss

In February 2003, I met a patient with severe bilateral vestibular loss due to gentamicin toxicity, and I felt disheartened. Despite the fantastic diagnostic vestibular lab we had at Maastricht University Hospital, what could I truly offer her? She had...

In space no-one can hear you scream…or can they?

Plasma, eardrums the size of planets and questioning the wisdom of your school physics teacher! Martin Archer explains the fascinating world of sound and space. Is there sound in space? If you believed the marketing of the movie Alien, or...