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Intraoperative identification of primary tumours in unknown primary head and neck cancer using transoral laser microsurgery with frozen sections

The aim of the study was to compare the sensitivity and specificity of intraoperative identification of primary tumours in patients with unknown primary head and neck squamous cell carcinoma (UP HNSCC) using transoral laser microsurgery (TLM) with frozen sections, with...

Olfactory protective effect of omega-3 supplements during healing after endoscopic sellar and parasellar resection

This multicentre study, led by researchers from Stanford, demonstrates another use for omega-3 supplements. The study analysed cohorts equally divided between control arm and omega-3 supplementation. Post endoscopic sellar and parasellar resection, better olfactory function was observed at three and...

The EU Medical Device Regulation (MDR)

Back in May 2017, the EU Medical Device Regulation (MDR 2017/745) entered into force, replacing existing directives: Active Implantable Medical Devices (AIMD) In-vitro Diagnostic Directive (IVDD) Medical Device Directive (MDD) By 26 May 2020, the new regulation will have completed...

Panetti Endoscopic Ear Instruments

Giuseppe Panetti is a renowned otologist and one of the forerunners of endoscopic ear surgery. One of his major contributions to ENT has been through designing bespoke equipment to assist in some of the challenges of operating endoscopically. In this...

Panetti Endoscopic Ear Instruments

Giuseppe Panetti is a renowned otologist and one of the forerunners of endoscopic ear surgery. One of his major contributions to ENT has been through designing bespoke equipment to assist in some of the challenges of operating endoscopically. In this...

Office-based otology procedures

This edition of the Otolaryngologic Clinics of North America covers office-based surgery in ENT. This article discusses procedures in otology that could be performed in the outpatient setting and covers innovations in office-based otologic procedures. The endoscope features prominently in...

Big data and the future of cochlear implant aftercare

With a million people using cochlear implants worldwide, the time is right for us to harness this vast data for patient benefit. Every day, cochlear implant (CI) processors quietly collect data: how long they’re worn, how often users switch programs...

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

The effects of leisure noise exposure on young people’s hearing

There is growing concern regarding the effects of leisure noise exposure on young people’s auditory system. Information provided by healthcare professionals should be evidence-based; Hannah Keppler discusses some recent findings about hearing in young people. Excessive noise exposure can lead...

Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?

Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...

Partial reconstruction of the pinna

Reconstruction of the pinna is one of the most challenging procedures in facial plastic surgery. Although there has been significant progress since one of the earliest recorded descriptions by Sushruta in 600 BC, the complex three-dimensional structure of the pinna...

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.