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Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Panetti Endoscopic Ear Instruments

Giuseppe Panetti is a renowned otologist and one of the forerunners of endoscopic ear surgery. One of his major contributions to ENT has been through designing bespoke equipment to assist in some of the challenges of operating endoscopically. In this...

Panetti Endoscopic Ear Instruments

Giuseppe Panetti is a renowned otologist and one of the forerunners of endoscopic ear surgery. One of his major contributions to ENT has been through designing bespoke equipment to assist in some of the challenges of operating endoscopically. In this...

Cochlear implantation in inner ear schwannoma patients

Inner ear schwannomas (IES) are rare. Patients with IES tend to lose their hearing. Surgery is a treatment option, but it leads to complete loss of hearing. Other treatment options include stereotactic radiosurgery (SRS) and watchful waiting (WW). The authors...

Random-pattern skin flaps: part 2 - rhomboid and bilobed flaps

In the second of our series on local skin flaps (see Part 1 here, Part 3 here and Part 4 here), the authors describe more techniques and examples of various skin flaps that trainees should find very interesting. Rhomboid flap...

The EU Medical Device Regulation (MDR)

Back in May 2017, the EU Medical Device Regulation (MDR 2017/745) entered into force, replacing existing directives: Active Implantable Medical Devices (AIMD) In-vitro Diagnostic Directive (IVDD) Medical Device Directive (MDD) By 26 May 2020, the new regulation will have completed...

Endoscopic Dacryocystorhinostomy

Epiphora, or abnormal tearing, occurs because of blockage in the lacrimal drainage system, which impairs normal tear channeling into the nose. Dacryocystorhinostomy (DCR) is used to treat patients diagnosed with lacrimal sac or nasolacrimal duct obstruction (NLDO). External DCR was...

Between sirens and silence: the burden on otorhinolaryngologists in wartime Ukraine

Ukrainian ENT teams continue life-saving and routine care under air raid alerts, with staff shortages, strained resources and the long psychological toll of war. War reshapes medicine long before it destroys hospitals. It alters the rhythm of clinical work, the...

Telehealth for cochlear implant follow-up care

For individuals with moderate-to-profound sensorineural hearing loss, cochlear implants are a highly effective form of hearing rehabilitation. Despite their effectiveness, utilisation is low, with approximately only 12.7% of suitable adult candidates receiving implants. Barriers to access include the geographic distribution...

Intraoperative identification of primary tumours in unknown primary head and neck cancer using transoral laser microsurgery with frozen sections

The aim of the study was to compare the sensitivity and specificity of intraoperative identification of primary tumours in patients with unknown primary head and neck squamous cell carcinoma (UP HNSCC) using transoral laser microsurgery (TLM) with frozen sections, with...

Big data and the future of cochlear implant aftercare

With a million people using cochlear implants worldwide, the time is right for us to harness this vast data for patient benefit. Every day, cochlear implant (CI) processors quietly collect data: how long they’re worn, how often users switch programs...