You searched for "genetic"

1457 results found

SPECT-CT imaging improves surgical efficiency in sentinel lymph node biopsy in melanoma

Sentinel lymph node biopsy is used in clinically lymph node negative, primary cutaneous melanoma. A combination of planer lymposcintigraphy using a radiolabelled colloid detected intra-op by gamma probe, and cutaneous injection of blue dye is used. However, with lymphoscintigraphy spillage...

Is bone cement a cost-effective solution?

This study looks at the functional results of 52 patients who underwent bone cement ossiculoplasty. Patients were divided into four groups based on ossicular disruption. Group 1 (30 patients) had lenticular erosion only. Group 2 (13 patients) had absent incus....

Stenting and sinus surgery

Stents are used in sinus surgery with the aim of maintaining patency of sinus cavity avoiding restenosis from inflammation or scarring. The exact indication for stenting in sinus surgery however is still debated. The authors discussed the potential role of...

Persistent dysphonia due to cricothyroid muscle dystonia – should we be requesting laryngeal EMGs for non-resolving ‘functional’ dysphonia?

This article is an interesting report of a case of persistent voice problems affecting a 43-year-old physician that significantly compromised her ability to converse and communicate at work. Specifically, she had a fluctuating voice quality that would ‘choke off’, combined...

Botulinum toxin injection for bilateral recurrent laryngeal nerve paralysis

All traditional surgical treatments for bilateral recurrent laryngeal nerve (RLN) paralysis are essentially a balance between maximising airway patency and ensuring adequate phonation / airway protection. This paper highlights the potential role of botulinum toxin (Botox) injection into the cricothyroid...

Cochlear implants for tinnitus

This study from Belgium is the first to look at the long term reduction in tinnitus for a cohort of 23 patients with unilateral profound hearing loss and incapacitating tinnitus implanted with cochlear implants (CI). The authors were able to...

Treating benign positional paroxysmal vertigo

Benign positional paroxysmal vertigo (BPPV) is one of the most common causes of dizziness. Its treatment is the repositioning of displaced otoliths by the canalith repositioning manoeuvre (CRM). Post manoeuvre restrictions are commonly given to the patient. Their benefit has...

Double suspension sutures for obstructive sleep apnoea

This study examines the benefit of an operation that targets the lateral pharyngeal wall. The double suspension sutures are, in essence, a suture through the palatopharyngeus muscle which is then tied around the hamulus in the retro molar area. This...

Hypoglossal nerve stimulation for OSA

Hypoglossal nerve stimulation has been lauded as the great new surgical treatment panacea for obstructive sleep apnoea (OSA). This meta-analysis includes 12 studies with a total of 350 patients, including the five-year follow-up data from the STAR trial which was...

Satisfaction levels in elderly patients with cochlear implants

Hearing rehabilitation in the elderly is of utmost importance as it is associated with depression and dementia in this age group. Cochlear implantation is indicated for hearing-impaired individuals who do not derive adequate benefit from conventional hearing aids. In this...

A new treatment for smell loss?

It has been well established that smell training can be effective in the recovery of smell function post Covid-19 infection, and many other treatment modalities have been assessed. There have been limited studies to date evaluating the effects of dietary...

Adenoid cystic carcinoma – insights from a national database

Adenoid cystic carcinoma (AdCC) is a rare cancer of the salivary glands that accounts for approximately 1% of all head and neck malignancies. Hallmarks of this cancer type include a predilection for perineural infiltration, a prolonged clinical course with late...