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Nasal deformity following CPAP injury

Nasal continuous positive airway pressure (nCPAP) is commonly used as a non-invasive alternative to endotracheal intubation and tracheotomy to provide respiratory support to very low birth weight (VLBW) (<1500 g) neonates. Nasal injury is a well recognised complication and figures...

Not so innocent, after all: a meta-analysis of the effects of intranasal corticosteroids on growth

The use of intranasal corticosteroids has revolutionised the management of allergic rhinitis and rhinosinusitis and there is now significant evidence of their safety. The problem with side-effects is that clinical studies are designed to demonstrate efficacy, but are underpowered to...

The sentinel lymph nodes revisited

The concept of sentinel lymph node sampling has been around for some time. However, its acceptability in routine head and neck practice has yet to be established. This article presents the authors’ experience in 10 patients with Merkel cell carcinoma...

Do you know what aphasia is?

In 2001 a survey was conducted in a number of towns across the world, including Exeter in the UK, to identify the level of awareness and knowledge of aphasia in the community. Aphasia is difficulty in producing or understanding language...

Anaesthesia for excision of vestibular schwannomas

The ‘shared airway’ relationship between ENT surgeons and anaesthetists is well documented. But ENT surgery and anaesthesia interact in numerous other ways, particularly in complex skull base surgery. What do our anaesthetic colleagues want us to know about vestibular schwannoma...

A place for everything and everything in its place: the practicalities of randomised clinical trials

Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...

The EU Medical Device Regulation (MDR)

Back in May 2017, the EU Medical Device Regulation (MDR 2017/745) entered into force, replacing existing directives: Active Implantable Medical Devices (AIMD) In-vitro Diagnostic Directive (IVDD) Medical Device Directive (MDD) By 26 May 2020, the new regulation will have completed...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

Audiological approach to treatment of blast-induced tinnitus

Hearing loss and tinnitus resulting from blast waves in the war zone is becoming more common in our clinics. Hamid Jalilvand based in Tehran, shares his experience in audiological rehabilitation and research findings on patients in his clinics with a...

Freud’s Friend, Fliess

Wilhelm Fliess, a Berlin rhinologist, was for many years Sigmund Freud’s closest friend and confidant. He was born in Poland in 1858. In 1887, he visited Vienna for postgraduate studies, and met the famous psychoanalyst, Freud [1]. They were immediate...

Introducing Otinova – A unique formula for Otitis Externa

Otinova Ear Spray is a medical device that treats ear canal inflammation/otitis externa, sometimes known as ‘swimmers ear’.

Bishop Berkeley and the Freireich experimental hypothesis

Our resident reporter at large tells us about two of his heroes, both of whom have quite clear merits and foibles. My patients just keep on getting better. You may well point out that under the care of a clinician...