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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Developing outcome measures for research

There are challenges in developing outcomes measures; Professor Hall presents five top pointers for making rapid progress in developing outcome measures for research purposes. Anyone who has worked clinically with hearing loss will appreciate that every patient’s experience is personal....

Hyperacusis and autism spectrum disorder

Several different auditory deficits have been found to be co-morbidities of ASD. This article reviews literature with respect to the relationship between hyperacusis and ASD. Autism spectrum disorder (ASD) can be characterised as a neurodevelopmental condition that is marked by...

The role of objective measures and imaging to optimise cochlear implant outcomes

Should we be using new or novel objective measures and imaging to assist with our cochlear implant patients? Debi Vickers and Shak Saeed describe current clinical techniques and present advances that have the potential to optimise outcomes. Introduction It is...

Cochlear implantation in children with single-sided deafness: rationale and early findings

Cochlear Implantation (CI) in children with single-sided deafness (SSD) is a controversial treatment option. Profs Karen Gordon, Papsin and Cushing discuss the rationale and early findings on the relative success of achieving binaural hearing for SSD with CI. If you’d...

Hearing loss and cognition: something to think about

Irace, Chern and Golub propose causal and non-causal mechanisms for the links between hearing loss and dementia, concluding with a discussion of several proactive measures available to help preserve neurocognitive health in older adults with hearing loss. What is age-related...

Chronic rhinosinusitis management: back to the future?

Immunology is a dim and distant medical school memory to many ENT surgeons, but the increasingly complex immunology of chronic rhinosinusitis is fascinating (honestly!). Medical management options in CRS no longer just involves saline and steroids, and we need to...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Commentary: dementia, hearing loss, and the danger of professional rabbit holes

The Lancet, a world-leading general medical journal, has a global impact. Its commissioned report into dementia prevention, intervention and care has been cited over 6000 times and has further been reviewed and updated in 2020 and now 2024. Here, Profs...