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Measuring radiation fibrosis in patients with head and neck cancer
People treated with radiotherapy for head and neck cancer experience several acute and chronic effects of this treatment, of which fibrosis is perhaps the most common. Fibrosis occurs as a wound healing response and leads to scarring and reduced range...
Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?
Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...The role of prediction and gain in tinnitus
Dr Will Sedley is a Clinical Academic Neurologist who has done groundbreaking work in the field of tinnitus mechanisms. Here, he introduces and explains the concepts of prediction and of gain as they relate to troublesome tinnitus. This article focuses...Quo vadis FESS? Future directions in functional endoscopic sinus surgery
Endoscopic sinus surgery is now so ubiquitous that it is hard to imagine a time when it was not part of our clinical practice. Valentin Tomazic takes a look at its early development and looks ahead to endoscopic sinus surgery...
