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Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...

Hyperacusis-related distress and comorbid psychiatric illness

Research suggests that over 50% of patients presenting with hyperacusis also present with some form of psychiatric disorder. With this in mind, Dr Aazh outlines what tools clinicians can use to screen for psychological disorders and what path to take...

Transnasal endoscopic orbital decompression

Surgery for the eye complications of Grave’s disease is an area that, over the years, ENT has become more and more involved in due to our ability to access the orbit endoscopically. In this article, the authors describe their technique...

Introducing the AOT Pod

Our Newsround editor Haseem Raja interviews Josh Michaels from the Association of Otolaryngologists in Training (AOT) to discuss the new podcast. Josh Michaels. Congratulations on creating The AOT Pod ! Tell us more about AOT and what inspired you to...

Parathyroidectomy

Many ENT head and neck surgeons are now involved in thyroid surgery. This can also include the need to explore the parathyroids, either to preserve them or indeed to resect parathyroid adenomas. David Smith, a highly experienced endocrine surgeon from...

From the editor Nov/Dec 2025

Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. TW / X: @Voicedoctor_uk For ENT&A Nov/Dec2025, we are delighted to celebrate the remarkable educational institution ENT Masterclass®, which marks its 20th anniversary with...

Papzimeos: a major advance in treating adult recurrent respiratory papillomatosis

Since the beginning of our specialty, generations of patients and surgeons have faced the challenging clinical problem of recurrent respiratory papillomatosis (RRP). Driven by a persistent and chronic infection with low-risk human papillomavirus (HPV) types 6 or 11, it is...

Mucormycosis: In conversation with Dr Deepak Haldipur and Dr Aditya Moorthy

COVID-19 has ravaged the world in the past 18 months. The second wave in many countries was deadlier than the first. Mucormycosis, infamously labelled ‘the black fungus’ has affected some countries, such as India, in epidemic proportions within this COVID...

Understanding the NAL-NL3 Prescription System: a new era of personalised hearing aid fitting

The NAL-NL3 system marks a transformative step in hearing aid fitting, shifting from a one-size-fits-most prescription to a modular, patient-centred approach. Developed by the National Acoustic Laboratories, this new system integrates a core audiogram-based prescription with targeted modules to address...

Selective upper airway stimulation

Obstructive sleep apnoea (OSA) is one of the most common diseases in industrialised countries and is characterised by an intermittent obstruction of the upper airway during sleep. The standard treatment for OSA is continuous positive airway pressure (CPAP) therapy, which...

Machine learning and the future of otolaryngology

If you are over 30 years of age, you have witnessed a technology revolution that has grossly affected how we live: computers have come from being an oddity to an everyday feature in our households and places of work; the...