5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...
As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...
The authors provide a comprehensive introduction to audiology for students and clinicians in audiology and related professions. The textbook has a favourable layout: chapters are organised logically and begin with a set of learning objectives providing a preview of what...
The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...
The head impulse test (HIT) is an essential bedside test to detect peripheral vestibular deficits. The video head impulse test (vHIT) is a new tool quantifying the HIT. In this article Maria Heuberger and colleagues point out the clinical utility...
Voice outcomes are the main comparators when managing unilateral vocal fold paralysis (UVP). In a review of the literature, 11 voice indicators are included in 80% of all articles. However, when surgeons were surveyed on their clinical preferences and their...
This study involves a province in Canada and claims that the need for paediatric myringotomy and insertion of grommets reduced to a third with public health measures aimed at reducing transmission of respiratory viruses, including SARS-CoV-2, in the Covid-19 pandemic....
Professor Philip Stell was an extraordinary man: following an astonishingly illustrious career in ENT, he excelled as a medieval historian. With the Philip Stell Prize due to be awarded in May, his friend Pat Bradley looks back at his remarkable...
This nice scientific paper pits various antiseptic solutions against each other to determine which has the most bactericidal properties. Five different antiseptics were applied to MRSA and quinolone-resistant pseudomonas species, which are both difficult to treat with conventional ototoxic medications....
This article presents findings of a retrospective evaluation of 489 patients who underwent vestibular schwannoma surgery and developed delayed facial palsy. The authors define delayed facial palsy as deterioration of at least two HB grades between postoperative days five and...
The large majority of sialorrhoea (drooling) in paediatric patients is managed conservatively. However in severe cases, often where there is associated developmental delay or a motor disorder, medical and surgical techniques can be used to decrease salivary flow. Botulinum toxin...