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The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

The role of objective measures and imaging to optimise cochlear implant outcomes

Should we be using new or novel objective measures and imaging to assist with our cochlear implant patients? Debi Vickers and Shak Saeed describe current clinical techniques and present advances that have the potential to optimise outcomes. Introduction It is...

Globe Trotting and 62 years of ENT

Vasant Oswal was, for many years, ‘Mister ENT’ in the Northeast of England. Appointed as a consultant to the old North Riding Infirmary in 1970, he led what was a small and little-known department through a period of tumultuous change...

Macrolinguistic assessment in early Alzheimer’s disease

Deficits in language production like word finding difficulty, and lexical-sematic impairment have been documented early in the course of Alzheimer’s disease (AD). According to the authors, the current language assessment methods used in AD patients do not account for macrolinguistic...

Diagnosing and managing somatic tinnitus

Interactions between auditory and somatosensory pathways can lead to interesting tinnitus experiences which can be very bothersome. Dr Sarah Michiels describes her pioneering work in this area, and the possibilities of physiotherapy based therapy. Background Somatic (also called somatosensory) tinnitus...

Cochlear implantation in Tanzania: the journey and the outcomes

It is estimated that over 400 million people worldwide live with disabling hearing loss, 39.9 million of whom live in sub-Saharan Africa [1]. This article by Dr Aveline Kahinga and Mr Ali Jaffer demonstrates the effort that has been made...

Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour

Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...

What has NAIROS taught us about septoplasty?

Septoplasty is a commonly performed procedure worldwide for nasal obstruction associated with a deviated nasal septum. In the UK, with long waiting lists for septoplasty, there is a large and unexplained variation in the incidence of this procedure between individual...

The future of hearing care and the role of audiology

The Clinical Director of Cincinnati Children’s Hospital Medical Center and President-elect of the American Academy of Audiology reviews the status of the present day audiologist’s remit, and discusses the changes we can expect with the changing demographic and behaviour of...

A Treatise on Otosclerosis and its Treatment

Rinze Tange and I were co-authors for the otosclerosis chapters of both the seventh and eighth editions of Scott-Brown’s Otorhinolaryngology which he references in his book. It was particularly exciting therefore to receive this beautiful 363-page treatise on all that...

Rapid Audiogram Interpretation: A Clinician’s Manual

This book is a manual and a workbook to systematically understand and interpret an audiogram for those who are new to audiometry such as residents, trainees and students. It is a worthy reference guide even to well-established practising clinicians. The...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...