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Muscle tension dysphagia: an underdiagnosed problem

In this article, the authors introduce the description of swallowing problems which have been recently attributed to muscle tension dysphagia (MTDg). The authors are clear that this is a diagnosis of exclusion, and it is important to rule out other...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Vestibular dysfunction after cochlear implantation in children

Whilst vestibular dysfunction is a known outcome of cochlear implant surgery, do we know the risk factors associated with this, particularly in children? In this article a team from University of Tokyo discuss their findings. Cochlear implantation (CI) is an...

Cell therapies for hearing loss

Cell therapies could offer a way to repair damage to the auditory system and reverse many types of hearing loss. This article looks at the progress being made.

Sugammadex

Scott Russell is an anaesthetist with an almost unrivalled experience of complex head and neck surgery, and has seen all manner of new ideas come and go. However, in this article he describes a new pharmaceutical agent that is already...

Advances in vestibular function testing

Vestibular function testing has historically been limited by difficulties in testing individual parts of the vestibular apparatus. Jas Sandhu describes new tests available to clinicians that address this problem. Advances in vestibular function testing Vestibular function testing has historically been...

Neural plasticity and aural rehabilitation

Neural plasticity refers to an ability of the brain and central nervous system to change their structure and function or their reorganisation in response to environmental cues, experience, learning, behaviour, injury and / or diseases and treatments. Neural plasticity is...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...