You searched for "Cell"

2293 results found

Intraoperative identification of primary tumours in unknown primary head and neck cancer using transoral laser microsurgery with frozen sections

The aim of the study was to compare the sensitivity and specificity of intraoperative identification of primary tumours in patients with unknown primary head and neck squamous cell carcinoma (UP HNSCC) using transoral laser microsurgery (TLM) with frozen sections, with...

Outcomes of larger glottic cancer volumes treated with radiotherapy

T3 glottic cancer is characterised as vocal cord fixation and/or invasion into pre-epiglottic, post-cricoid, paraglottic spaces and/or within the inner cortex of thyroid cartilage. Traditionally, laryngectomy was considered the primary option to treat T3 laryngeal glottic cancers until other options...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Radiology of referred otalgia

Otalgia is a common presenting complaint to Ear Nose and Throat Departments. Otalgia is either primary or secondary (referred) [1]. Referred otalgia is a ‘red flag’ symptom and can be a diagnostic challenge for clinicians and radiologists as the pathology...

Biofilms in Otitis

If you haven’t already heard of biofilms, this book will tell you that they are multicellular networks of bacteria encased in a matrix, a complex multidimensional biologic fortress that protects bacteria against changes in the environment, host immune responses and...

In conversation with Chrysa Spyridakou, Robert Nash, Emma Clement, Nish Mehta and Anne GM Schilder

Jaclyn Tan interviews members of the London-based multidisciplinary hearing team, about their insights to auditory neuropathy spectrum disorder, and their vision for the future management of this challenging range of conditions. Auditory neuropathy spectrum disorder (ANSD) describes a wide range...

Mentally and physically safe workplaces: the challenge of doctors’ well-being

Our ENT consultant colleague Eric Levi bravely tackles the very real elephant in the room of that stigma which is not really discussed until it is often too late. It takes courage to tackle a difficult topic like doctors’ mental...

Spasmodic dysphonia – is greater awareness needed?

Spasmodic dysphonia (SD) is a focal dystonia of the laryngeal musculature. Previously considered to be a rare disorder, it has more recently been suggested that SD is in fact not rare but is frequently misdiagnosed or undiagnosed. This paper would...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Smart cochlear device: how biosensors could revolutionise hearing care

Smart cochlear implants could monitor inner ear health, deliver drugs and adapt in real time, merging biosensing, microfluidics and personalised hearing care. From passive hearing aids to smart implants Hearing technology has advanced dramatically over the last few decades, yet...

Fitting and Dispensing Hearing Aids, Second Edition

As you might expect from two authors of such stature, this book is extremely effective and well written. In form it is as close to a pop-science book as one could get while still being very much focussed for those...

Can we tell the difference between benign recurrent vertigo, migraine and Menière’s disease?

I chose to review this article as it reminds us of the difficulties in diagnosing dizzy patients accurately and the significant crossover of symptoms between the diagnoses. Does Benign Recurrent Vertigo (BRV) even exist as a separate entity? BRV is...