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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Laryngotracheal stenosis

Airway stenosis has been an enormous challenge to laryngologists since the dawn of the sub-specialty. Careful evaluation is essential, as this will determine the best treatment. We hear more from one of the UK’s leading airway centres. Until the advent...

Airway stenting in paediatric ENT

Although experience in the use of airway stents in adults is considerable, their use in children is more recent and more limited. Cláudia Schweiger and Michael J Rutter provide an overview of stents and their use in paediatric airway. Stenting...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

Advanced in-office awake rhinology

In-office awake rhinology transforms sinonasal care, offering safe, cost-effective, minimally invasive procedures with rapid recovery and high patient satisfaction. In recent years, the landscape of otolaryngological surgery has undergone a remarkable transformation with the advent of in-office awake surgical procedures....

Unravelling the mystery of hyperacusis with pain

When a person says that sound causes them pain, how can we understand this, and determine what processes are involved? Bryan Pollard navigates us through what is presently known. Pain has long been underrepresented – and often, completely overlooked –...

EEG as a measure of neuroplasticity in children

Measuring changes in neural activity can teach us a lot about hearing loss and the effect of gained functional hearing. In this article, the authors describe how electroencephalography (EEG) is being used to effectively measure such changes in children with...

Plasticity with cochlear implants: individual factors in the outcomes

Andrej Kral gives us an overview of neuronal plasticity in congenital hearing loss, and discusses why it is core to our clinical interventions in hearing loss and rehabilitation. The brain is born immature and undergoes extensive shaping during early development....

Imaging and management of head and neck vascular anomalies

Vascular anomalies are a diffuse spectrum of abnormalities which often involve the head, neck and oral cavity. They are frequently misnamed, often being generically labelled as haemangiomas. This lack of basic understanding can cause confusion leading to a cascade of...

In conversation with Professor Jos Eggermont

Having known Jos for many years, I jumped at the opportunity to catch up with him for our Nov/Dec 2020 series of tinnitus items. My questions reached him during lockdown, and he was enjoying the chance to get on top...