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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
Predicting the nature of swallowing deficits caused by surgical resection of the tongue?
Patients treated surgically for cancer of the tongue are expected to have difficulty in eating, drinking and swallowing. The authors of this paper report on a cohort of 106 patients in their practice who had surgical resection as primary treatment....In conversation with Professor David Kemp
Ted Killan, Vice-Chair of the British Society of Audiology (BSA), caught up with Professor Kemp to discuss his scientific journey over the past 40 years, and what we can expect from OAEs in the future. Prof David T Kemp. In...MDT clinics for adults with learning disabilities and hearing loss
Healthcare providers can have limitations and challenges providing optimum care for patients with intellectual disabilities. Siobhan Brennan and Susanna Goodhart highlight key professionals and carers who may be instrumental when trying to deliver good management and care along with other...Shooting for Gold: ENT surgery and the Commonwealth Games
What are the secrets to success in your career, sports and life in general? Sharp-shooter Parag Patel hits the bullseye again. I write this article following a wave of summer sporting brilliance, from the record Great Britain 67 medal haul...
Management of stage IV pharyngolaryngeal lesions
This is a retrospective study of 63 patients presenting with stage four laryngeal and/or hypopharyngeal squamous cell carcinoma. The aim was to define the factors influencing the oncological and functional outcomes of the patients. All patients had T4 lesions with...
Intermediate risk factors SCC tongue
This retrospective review from Japan assessed 89 patients who underwent surgery for squamous cell carcinoma of the tongue, specifically they reviewed the evidence of perineural and vascular invasion (27.0% and 23.6%). Their results suggest, not unsurprisingly, that perineural and vascular...
Free flap reconstruction in stage three bisphosphonate-related osteonecrosis
There is no widely accepted gold standard for the treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ). Early BRONJ is managed conservatively but there is controversy regarding the treatment of the later stages. Stage three is defined as exposed bone...Database WG2. The Tinnitus Patient Database in the TINNET COST Action BM1306
Berthold Langguth describes an innovative project that is creating the world’s largest multi-national patient database containing standardised information on tinnitus and medical history, otological examination and psycho-acoustic measures of tinnitus. A challenge for tinnitus treatment and tinnitus research is the...
Damage to the cochlear nucleus with electrocautery to the cochlear nerve
This study is of importance to neurotologists and neurosurgeons. It is unclear why patients with NF2 have poorer outcomes with an auditory brainstem implant compared to non-tumour patients. This effect is postulated to be due to damage to certain cells...
When to treat a fractured mandible?
This is a prospective study from Brisbane of 215 patients with a total of 359 fractures of the mandible. Nine outcome variables were analysed with a further 19 included to adjust for potential confounding. Treatment delay was found not to...
